Ondero-D 10 Tablet

CompleteOndero-D 10 Tablet
: Usage and Insight

Ondero-D 10 Tablet – Introduction

Ondero-D 10 Tablet is a combination of two antidiabetic medications: dapagliflozin and linagliptin, in strengths of 10mg and 5mg, respectively. Dapagliflozin works by lowering blood sugar levels in people with type 2 diabetes by promoting the excretion of extra sugar from the body through urine. Linagliptin works by increasing the amounts of certain natural substances that lower blood sugar when it is high.

How Ondero-D 10 Tablet Works: A Closer Look

Ondero-D 10 Tablets’ mechanism of action can be broken down into two categories as follows:

• Dapagliflozin: It inhibits the sodium-glucose cotransporter 2 (SGLT2) in the kidneys, leading to increased urinary excretion of glucose. This helps lower blood sugar levels.
• Linagliptin: It stimulates insulin release and decreases the release of glucose into the bloodstream.

Use

In the Management of Type 2 Diabetes Mellitus in adults

Ondero-D 10 Tablet – The Benefits

Ondero-D 10 Tablet helps control high blood glucose (sugar) levels in patients with diabetes. Lowering blood glucose levels is essential for managing diabetes and preventing complications such as kidney damage, blindness, heart attacks, and strokes. Taking this medicine regularly, along with proper diet and exercise, contributes to a normal, healthy life.

Ondero-D 10 Tablet – A Usage Guide

• Take 5 mg of dapagliflozin orally once daily.
• Increase to 10 mg daily if additional glycemic control is needed and well-tolerated.
• For combination therapy, take 1 tablet (10 mg dapagliflozin + 5 mg linagliptin) every morning.
• Correct any volume depletion before starting therapy.
• Ensure eGFR is above 45 mL/min/1.73 m² to maintain efficacy.
• Adjust insulin or secretagogue doses to reduce hypoglycemia risk when used together.
• Swallow the tablet whole with water—do not crush, chew, or break it.
• Take the tablet after your first meal of the day.
• Use as an adjunct to diet and exercise for type 2 diabetes management.
• Helps reduce the risk of hospitalization for heart failure in patients with cardiovascular risks.

Ondero-D 10 Tablet – Side Effects

Most adverse effects disappear when your body gets used to the medication and don’t require medical attention. See your physician if they continue or if you have concerns about them.

Common Side Effects:

• Dapagliflozin: Diarrhea, Headache, Dizziness, Hypoglycemia (low blood sugar), Nausea, Vomiting
• Linagliptin: Pain and burning during urination, Feeling light-headed, Low blood sugar symptoms including headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky

[Note: Various medications can lead to different side effects. For precise details about a particular drug’s specific side effects, consult the official prescribing information for that medication or seek advice from your healthcare provider.]

Ondero-D 10 Tablet – A Guide to Safety

Alcohol

Consult Your Doctor
Factors that may predispose patients taking Dapagliflozin to lactic acidosis include low beta cell function reserve (e.g., patients with type 2 diabetes who have low C-peptide levels, latent autoimmune diabetes in adults [LADA], or a history of pancreatitis). Remember to consult your doctor for the same.

Pregnancy

Unknown (Consult Your Doctor)
For Dapagliflozin and Linagliptin combination, it is unknown whether it can be given to pregnant women or breastfeeding mothers. If you fall into either category, please consult your doctor.

Breastfeeding

Unknown (Consult Your Doctor)
Limited data is available on the effect of Dapagliflozin+Linagliptin on breastfeeding. If you are a nursing mother, informing your doctor before taking this combination is essential. Your doctor will consider the benefits versus the risks.

Driving

Caution
If your blood sugar is too low or too high, it might impair your driving ability. If you experience these symptoms, refrain from driving.

Liver

Consult Your Doctor
There is no specific information on liver interactions for this combination in Ondero-D 10 Tablet. However, as a general precaution, patients with liver

isease should be monitored closely while taking any medication.

Kidney

Caution
It’s important to keep in mind that both Dapagliflozin and Linagliptin are mainly eliminated from the body through the kidneys. This is why it’s crucial to take into account their administration in individuals with impaired kidney function. It’s advisable to seek advice from your doctor.

 Fact Box

Swift Advice

• Seek medical care if you experience severe upper stomach pain spreading to your back, nausea, vomiting, or loss of appetite, as these could be signs of pancreatitis.
• Tell your doctor if you get unusually thirsty, pass urine more frequently, or feel tired. These are signs of too much sugar in your blood, and your dose may need to be adjusted.
• Dapagliflozin increases urinary glucose excretion by inhibiting SGLT-2 in the kidneys. In patients with kidney impairment, dose adjustments may be necessary to avoid excessive glucose excretion.
• Take it as directed, even if you skip a meal. Carry sugary food or juice for potential low blood sugar (symptoms include sweating and dizziness).
• Discontinue the medication before undergoing any surgical procedures requiring anesthesia.
• Consult a healthcare provider, as the safety of the Dapagliflozin and Linagliptin combination during pregnancy and breastfeeding needs careful consideration.
• SGLT-2 inhibitors, including dapagliflozin, are associated with an increased risk of genital mycotic infections (such as yeast infections). Patients should maintain good hygiene and seek medical attention if symptoms occur.
• The risk of hypoglycemia may increase when combined with insulin or sulfonylureas.