Description
Istamet XR Tablet
Medicine | Istamet XR Tablet |
Marketed By | Sun Pharmaceutical Industries Ltd |
Active Ingredient | Sitagliptin 100mg and Metformin 1000mg |
Storage | Store below 30°C |
Consume Type | Oral |
Istamet D -IR Tablet – Introduction
Istamet D IR Tablet contains dapagliflozin, sitagliptin, and metformin—three powerful ingredients that help lower high blood sugar in type 2 diabetes. They work by reducing sugar made by the liver, improving insulin use, increasing insulin release, and helping the body remove extra sugar through urine.
How Istamet D -IR Tablet Works: A Closer Look
In order to lower blood sugar, metformin primarily inhibits hepatic gluconeogenesis, an intrinsic process that raises blood glucose levels, as well as the action of glucagon. Sitagliptin also inhibits dipeptidyl peptidase-4 (DPP-4), which increases the levels of incretin hormones (like GLP-1 and GIP). These incretins lower blood sugar by stimulating the production of more insulin by pancreatic beta cells and reducing the amount of glucagon released by pancreatic alpha cells. Dapagliflozin, by inhibiting Sodium-glucose co-transporter 2 (SGLT2), increases urinary glucose excretion and lowers blood glucose levels.
Use
Mangement of Type II Diabetes Mellitus
Istamet D -IR Tablet – The Benefits
In Management of Type II Diabetes Mellitus
Istamet D IR is a medication that helps people with type II diabetes better control their increased blood sugar levels. For optimal outcomes, this drug should be used in conjunction with dietary modifications and physical activity.
Controlling blood sugar levels can help avoid problems like renal disease, nerve damage, blindness, amputations, and sexual dysfunction. Reducing the chance of heart attacks and strokes is another benefit of effective diabetes control.
Istamet D -IR Tablet – A Usage Guide
- Pay attention to your doctor’s advice regarding the dosage and timing of this medication’s administration. Swallow the tablet whole along with some water. Never chew them. It must be taken in conjunction with food to avoid stomach upset.
- When you remember to take the missed dose, do so right away. However, if it’s almost time for your next prescription, skip the one you skipped and resume your regular regimen. It is not recommended to take two dosages at once.
Istamet D -IR Tablet – Side Effects
The majority of the side effects fade away as your body adjusts to the medication. If they persist longer than expected it is advisable to book an appointment with your doctor.
Common Side Effects
- Nausea
- Urinating more frequently than usual
- Vomiting
- Thrush
- Back pain
- Metallic taste in the mouth
- Diarrhea
- Stomach ache
- Altered appetite
[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s side effects, refer to the official prescription information or consult your healthcare provider.]
Istamet D -IR Tablet – A Guide to Safety

Alcohol
Unsafe
Do not consume alcohol while taking Istamet D IR Tablet to prevent lactic acidosis, a potentially fatal condition caused by an accumulation of lactic acid in the body.
Pregnancy
Consult your doctor
Istamet D IR 1000 might not be suitable to use when expecting. Studies involving humans are uncommon. However, research on animals has demonstrated negative effects on the growing fetus. Your physician will assess the advantages above any possible drawbacks before to prescription.
Breastfeeding
Consult your doctor
It might be dangerous to use it while nursing. Because the medication can enter breast milk, there is a lack of human data to support the idea that it could harm the infant.
Driving
Caution
It can be dangerous to drive when your blood sugar level is too high or too low. If you have any of these symptoms, avoid driving.
Liver
Unsafe
It is best to avoid taking Istamet D IR Tablet Dosage in individuals who have liver issues due to the possibility of adverse effects. Kindly speak with your doctor.
Kidney
Caution
Those with kidney conditions should use Istamet D IR Tablet Dosage cautiously. It could be necessary to change the dosage. Kindly speak with your physician. However, in those with severe kidney disease, however, it is not advised.
Fact Box
Chemical Group | Biguanide, Triazolopiperazine derivative, and C-glycosyl |
Addictive | No |
Medication Class | Biguanides, dipeptidyl peptidase-4 (DPP-4) inhibitor, and Sodium-glucose co-transporter 2 (SGLT2) inhibitor |
Action Class/Category | Type II Diabetes Mellitus |
Swift Advice
- Eat a balanced diet and exercise frequently to help lower blood sugar levels.
- Take it with food to minimize the chance of having a stomach upset.
- The adverse effects of this drug are less common than those of other diabetic treatments. Hypoglycemia and weight gain.
- Renal function tests should be conducted frequently when taking Istamet D IR.
- Be cautious to monitor your blood sugar levels while using this medication closely. If you experience nausea, vomiting, deep or rapid breathing, or stomach pain, contact your doctor immediately. These symptoms may indicate lactic acidosis, an uncommon but potentially fatal disease caused by an excess of lactic acid in the blood.
- Keeping sugar candies handy is a smart idea in case your blood sugar drops unexpectedly.
Does sitagliptin and metformin help you lose weight?
Metformin and sitagliptin have been shown in a few small studies to inhibit weight reduction, although there is no concrete evidence to support this claim. If you find that you are unexpectedly losing weight while undergoing therapy, consult your physician.
When is the best time to take Istamet XR?
Follow your doctor’s instructions regarding the best times and amounts to take Istamet XR. Consume it with meals to reduce the possibility of experiencing stomach distress. For optimal effects, it should be taken every day at the same time
Should I take Istamet XR before or after food?
Take Istamet XR with food to lessen the chance of suffering an upset stomach. It should be taken at the same time each day for the best results.
How long does it take for sitagliptin and metformin to lower blood sugar?
It may take months for the effects of metformin and sitagliptin in Istamet XR Tablet to fully manifest, even though they may start to show effects in as little as a week.
Where can Istamet XR Tablet be purchased in bulk?
You can purchase Istamet XR Tablet directly from reliable distributors and suppliers such as The Lotus Biotech. Utilize our online platform to search for and purchase high-quality drugs in large quantities. Depending on the quantity and your particular needs, contact us at info@thelotusbiotech.com for custom quotes.