Description
| Medicine | Vosicaz 200mg Injection |
| Marketed By | Glenmark Pharmaceuticals Ltd. |
| Active Ingredient | Voriconazole 200mg |
| Storage | Store below 25°C, Do Not Freeze |
| Consume Type | Intravenous Infusion |
Vosicaz 200mg Injection- Introduction
Voriconazole injection dosage is a treatment option for a range of serious, occasionally fatal fungal infections of the mouth, throat, and lungs. It is not recommended for usage by anyone with a history of sensitivity.
How Vosicaz 200mg Injection Works: A Closer Look
The voriconazole 200 mg injection works by inhibiting 14 alpha-lanosterol demethylation, a critical step in manufacturing fungal ergosterol mediated by fungal cytochrome P-450. If this critical stage is impeded, the fungal organism dies.
Vosicaz 200mg Injection – Use
Treatment of Severe Fungal Infections
Vosicaz 200mg Injection – The Benefits
In the Treatment of Severe Fungal Infections
Voriconazole injection dosage work against serious and potentially fatal fungal infections by functioning as a fungistatic agent.
Vosicaz 200mg Injection – A Usage Guide
It will be administered in a hospital setting by a medical professional.
Vosicaz 200mg Injection – Side Effects
Most of the voriconazole side effects fade away as your body adjusts to the medicine. If they persist longer than expected, booking an appointment with your doctor is advisable.
Common Side Effects
- High or low blood pressure
- Fast heart rate
- Electrolyte imbalance
- Stomach pain, bloating
- Nausea
- Kidney problems
- Pain at the injection site
[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s side effects, refer to the official prescription information or consult your healthcare provider.]
Vosicaz 200mg Injection – A Guide to Safety
Alcohol
Consult your doctor
Alcohol use may cause levels of voriconazole 200 mg injection to fluctuate due to modifications in liver metabolism. Avoid combining it with alcohol.
Pregnancy
Unsafe
Voriconazole injection dosage is categorized as pregnancy category D due to its teratogenic effects in animals. It’s strongly advised to avoid it during pregnancy unless the benefits outweigh the risks to the baby’s development.
Breastfeeding
Consult your doctor
There is no information available regarding the use of the injection while nursing. If the mother needs the medication, it is not a reason to cease nursing. Until more information is available, it could be preferable to use an alternative medicine, especially if you are nursing a newborn or a premature baby.
Driving
Unsafe
It could cause impaired vision and increase your sensitivity to strong light. Avoid working machinery during the day if your vision is hazy, and avoid driving at night.
Liver
Caution
It has been linked to increased abnormal liver function test results as well as symptoms of liver disease, such as jaundice. Injectable voriconazole should only be administered with severe hepatic impairment when the advantages outweigh the possible risks.
Kidney
Caution
According to current guidelines, people with renal impairment should not receive intravenous voriconazole.
Fact Box
| Chemical Group | Triazole antifungal |
| Addictive | No |
| Medication Class | 14-alpha Demethylase Inhibitors |
| Action Class/Category | Fungal Infection |
Swift Advice
- A certified medical practitioner should give it in a hospital environment. Observe all advice given to you by your doctor.
- Before using this medication, disclose your medical history and current medications to your doctor.
- Schedule routine testing for the liver and kidneys.
- An injection of the antifungal voriconazole may cause visual issues like light sensitivity and blurriness. Wear sunglasses during the day to protect your eyes from glaring light.
How many days is Vosicaz 200mg inj given for?
It depends on the type and severity of fungal infection. However, The median duration of treatment: Intravenous 10 days (range 2-90 days); orally 76 days (range 2-232 days). To get the most benefit, the injection should be administered at evenly spaced times and continued until the prescribed course is finished, even if symptoms disappear after a few days.
When should voriconazole injection be given?
The timing of voriconazole injection administration varies depending on the type of fungal infection. For fungal infections in adults, children aged 12 to 14 weighing 50 kilograms (kg) or more, and children 15 years and older, an initial loading dose is typically administered by the doctor within the first 24 hours of treatment.
Subsequently, the doctor may transition to an oral maintenance dose of 200 milligrams (mg) taken every 12 hours. Dosage adjustments may be made as necessary. It’s crucial to administer the injection at evenly spaced intervals and continue the treatment until completing the prescribed course, even if symptoms improve within a few days.
What effects does voriconazole have on the liver?
Voriconazole is associated with a risk of liver toxicity. Clinical trials have shown that some individuals experienced serious hepatic reactions, including hepatitis and fulminant hepatic failure, while taking voriconazole, with some cases resulting in fatalities.
Is voriconazole a steroid?
No, voriconazole is not a steroid. It is a triazole antifungal medication that exhibits fungistatic activity against fungal pathogens. Voriconazole functions by binding to 14-alpha sterol demethylase, also known as CYP51, inhibiting the demethylation of lanosterol in the ergosterol synthesis pathway of yeast and other fungi, ultimately leading to fungal death.
Who is the authorized distributor for Vosicaz 200mg inj?
The Lotus Biotech is a premier distributor of pharmaceuticals from India, renowned for our commitment to quality and dependable supply chains. As authorized distributors, we adhere to government regulations and ensure the availability of Vosicaz 200 mg Injections in bulk on a global scale. For inquiries regarding bulk orders, please contact us at info@thelotusbiotech.com.
