Description
| Medicine | Coliwin R Capsule |
| Marketed By | Mankind Pharma Ltd. |
| Active Ingredient | Chlordiazepoxide 5mg + Clidinium 2.5mg + Dicyclomine 10mg + Rabeprazole 10mg |
| Storage | Store below 30°C |
| Consume Type | Oral |
Coliwin R Capsule- Introduction
Coliwin R Capsule is prescribed for IBS, which can cause abdominal pain, bloating, and altered bowel habits. It combines the following drugs:
- Chlordiazepoxide: A benzodiazepine that helps manage emotional distress related to stomach disorders.
- Clidinium: Reduces stomach acid and intestinal spasms.
- Dicyclomine: Relieves intestinal cramping.
- Rabeprazole: A proton pump inhibitor that reduces stomach acid production.
The combination of these drugs helps address both physical symptoms and emotional distress associated with IBS.
How Coliwin R Capsule Works: A Closer Look
The mechanism of action of Coliwin R Capsule can be elaborated as follows:
Chlordiazepoxide:
Class: Benzodiazepine
Mechanism:
- Chlordiazepoxide acts on gamma-aminobutyric acid (GABA) receptors in the central nervous system.
- It enhances the inhibitory effects of GABA, leading to reduced anxiety and emotional distress.
- In the context of IBS, it helps manage emotional symptoms associated with gastrointestinal discomfort.
Clidinium:
Class: Anticholinergic
Mechanism:
- Clidinium blocks muscarinic receptors in the gut and other organs.
- By doing so, it reduces stomach acid secretion and intestinal spasms.
- This helps alleviate cramps and discomfort associated with IBS.
Dicyclomine:
Class: Antispasmodic
Mechanism:
- Dicyclomine is an anticholinergic agent that acts on muscarinic receptors.
- It relaxes smooth muscles in the gastrointestinal tract, particularly the intestines.
- By reducing muscle contractions, it relieves intestinal cramping and pain.
Rabeprazole:
Class: Proton Pump Inhibitor (PPI)
Mechanism:
- Rabeprazole inhibits the proton pump (H+/K±ATPase) in the stomach lining.
- This reduces gastric acid production by blocking the final step of acid secretion.
- Lower acid levels help manage symptoms like heartburn and acid reflux associated with IBS.
Coliwin R Capsule – Use
Coliwin R capsule uses can be listed as follows:
- Treatment of irritable bowel syndrome (IBS).
- Emotional distress related to stomach disorders.
- Relief from abdominal pain, cramps, and bloating.
Coliwin R Capsule – The Benefits
- Coliwin R Capsule provides relief from IBS symptoms, including pain, bloating, and altered bowel patterns.
- It addresses both physical and emotional aspects of the condition.
Coliwin R Capsule – A Usage Guide
- Take a capsule orally as directed by your doctor.
- Coliwin R dosage depends on age, medical condition, and response to treatment.
- Follow the medication guide provided by your pharmacist.
- Be cautious if you experience drowsiness or dizziness, especially if you’re an older adult.
- Report any unusual side effects promptly to your doctor.
- If you stop using Coliwin R suddenly, watch for withdrawal symptoms and seek medical help if needed
Coliwin R Capsule – Side Effects
Most side effects associated with the combination resolve on its own with extended usage. However, if persistent, consult your doctor immediately. Some common Coliwin R side-effects are as follows:
Common Side Effects
- Nausea
- Constipation
- Stomach pain
- Diarrhea
- Flatulence
- Dryness in the mouth
- Blurred vision
- Drowsiness
- Impaired coordination
- Confusion
- Headache
- Dizziness
- Flu-like symptoms
- Weakness
- Difficulty in urination
Precautions and Considerations:
- Avoid alcohol consumption during treatment with Coliwin R due to an increased risk of severe adverse effects (such as confusion, dizziness, nausea, vomiting, weakness, and fainting)
- If you experience any concerning side effects, promptly consult your doctor.
[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s side effects, refer to the official prescription information or consult your healthcare provider.]
Coliwin R Capsule – A Guide to Safety
Alcohol
Unsafe
It is unsafe to consume alcohol while taking Coliwin R Capsules. Alcohol can worsen the symptoms associated with this medication, such as dizziness and sleepiness.
Pregnancy
Unsafe (Consult Your Doctor)
Coliwin R Capsule is unsafe to use during pregnancy. There is definite evidence of risk to the developing baby. However, a doctor may prescribe it in some life-threatening situations if the benefits outweigh the potential risks.
Breastfeeding
Consult your doctor
Consult your doctor before using this medicine while breastfeeding. Although there is evidence of risk to the developing baby, the doctor may rarely prescribe it in certain situations
Driving
Unsafe
Coliwin R Capsule may cause dizziness and sleepiness. Avoid driving or engaging in activities that require mental focus until you know how this medicine affects you
Liver
Consult your doctor
If you have liver disease, take Coliwin R Capsule with caution. Your doctor may need to adjust the dose accordingly.
Kidney
Consult your doctor
If you have kidney disease, take Coliwin R Capsule with caution. Your doctor may need to adjust the dose accordingly.
Fact Box
| Chemical Group | Benzodiazepines, Anticholinergic, and Proton Pump Inhibitor (PPI). |
| Addictive | No |
| Medication Class | Antispasmodic agent and Anti-secretory drugs |
| Action Class/Category | Gastrointestinal |
Swift Advice
- Main Use: Treats irritable bowel syndrome symptoms.
- Before Surgery/Dentist: Let your doctor know about Coliwin R as it affects anesthesia.
- Medical Conditions to Discuss: If you have prostate problems, glaucoma, or urination difficulties, let your doctor know.
- Pregnancy/Breastfeeding: Inform your doctor if you are pregnant or breastfeeding.
- Caution for Seniors: Be careful if you’re over 65, as side effects can happen.
- New or Worsening Symptoms: See your doctor if you experience new symptoms or your condition worsens.
How to take Coliwin-R capsule?
You should not take Coliwin-R capsule without consulting a doctor. They will decide the appropriate dosage and instruct you. The general information found online mentions that Coliwin-R is typically taken orally, swallowed whole with water. Some sources suggest taking it on an empty stomach, while others recommend taking it with food. It’s important to follow your doctor’s specific instructions.
How long does it take for Coliwin-R capsule to work?
The exact timeframe for Coliwin-R to work can vary depending on the individual and the severity of their symptoms. Some people may experience relief within a few days, while others may take a week or longer to feel the full effects. It’s important to be patient and take the medication as prescribed by your doctor. If you don’t see any improvement as time passes, visit your doctor again.
How effective is Coliwin-R capsule for irritable bowel syndrome?
Coliwin-R capsule combines ingredients to address different aspects of irritable bowel syndrome (IBS). Chlordiazepoxide helps manage anxiety, which can worsen IBS symptoms. Clidinium and Dicyclomine relax muscles in the digestive tract, reducing cramping and pain. Rabeprazole reduces stomach acid, which can irritate the gut in some IBS cases. Studies have shown that Coliwin-R can be effective in managing IBS symptoms. However, individual experiences may be different.
Can Coliwin-R capsule be taken on an empty stomach?
There is conflicting information available online regarding whether to take Coliwin-R on an empty stomach or with food. It’s best to ask your doctor for specific instructions based on your needs. One can also take it on an empty stomach for faster absorption, or take it with food to reduce the risk of stomach upset.
Where to buy Coliwin R in bulk?
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