Description
Medicine | Istamet D -XR 1000 Table |
Marketed By | Sun Pharmaceutical Industries Ltd |
Active Ingredient | Dapagliflozin 10mg, Sitagliptin 100mg and Metformin 1000mg |
Storage | Store below 30°C |
Consume Type | Oral |
Istamet D-XR 1000 Tablet – Introduction
Istamet D XR 100/10/1000 consists of dapagliflozin, metformin, and sitagliptin. This potent antidiabetic composition helps individuals with type II diabetes lower their increased blood sugar levels. It decreases the amount of glucose produced by the liver, raises insulin sensitivity, and decreases intestinal glucose absorption.
How Istamet D-XR 1000 Tablet Works: A Closer Look
The mechanism of action of Istamet D XR 1000 Tablet includes: Metformin primarily inhibits the effects of glucagon and hepatic gluconeogenesis, a natural process that elevates blood glucose levels, thereby lowering blood sugar. Moreover, sitagliptin inhibits dipeptidyl peptidase-4 (DPP-4) to raise the levels of incretin hormones, including GLP-1 and GIP. By increasing the amount of insulin produced by pancreatic beta cells and decreasing the amount of glucagon released by pancreatic alpha cells, these incretins help lower blood sugar levels. Dapagliflozin decreases blood glucose levels and raises glucose excretion in urine by blocking sodium-glucose co-transporter 2 (SGLT2).
Use
Mangement of Type II Diabetes Mellitus
Istamet D-XR 1000 Tablet – The Benefits
In Management of Type II Diabetes Mellitus
People with type II diabetes can better regulate their increased blood sugar levels by taking sitagliptin + dapagliflozin + metformin dosage combined in Istamet D XR 1000 Tablet. For optimal effects, this medication should be used in conjunction with a balanced diet and regular physical activity. By keeping blood sugar levels within normal ranges, problems including erectile dysfunction, blindness, amputations, nerve damage, and kidney disease can be avoided. Reducing the chance of heart attacks and strokes is another benefit of effective diabetes control.
Istamet D-XR 1000 Tablet – A Usage Guide
- Regarding the dosage and timing of the tablet administration, heed the advice of your physician. Swallow the tablet completely and drink some water. Never chew them. To prevent an upset stomach, it is recommended to take it with food.
- Take the missed dosage as soon as you remember to. But if your next prescription is almost due, skip the one you missed and go back to your usual schedule. Taking two dosages at once is not advised.
Istamet D-XR 1000 Tablet – Side Effects
The majority of the side effects fade away as your body adjusts to the medicine. If they persist longer than expected it is advisable to book an appointment with your doctor.
Common Side Effects
- Nausea
- Urinating more frequently than usual
- Vomiting
- Thrush
- Back pain
- Metallic taste in the mouth
- Diarrhea
- Stomach ache
- Altered appetite
[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s side effects, refer to the official prescription information or consult your healthcare provider.]
Istamet D-XR 1000 Tablet – A Guide to Safety

Alcohol
UnsafeAvoid alcohol while using this medication to prevent lactic acidosis, a potentially fatal condition caused by a buildup of lactic acid in the body.

Pregnancy
Consult your doctorIt may not be suitable for use during pregnancy. Human subjects in studies are rare. Nonetheless, studies conducted on animals have indicated detrimental impacts on the developing fetus. Your doctor will weigh the benefits above any potential risks before writing a prescription.

Breastfeeding
Consult your doctorUsing it during nursing could be dangerous. Because the medication can get up in breast milk, there is not enough human data to support the theory that it could be hazardous to the newborn.

Driving
CautionDriving may be dangerous if your blood sugar is too high or too low. If you have any of these symptoms, don’t drive.

Liver
UnsafeBecause of the potential for negative consequences, it is advised to avoid taking the tablet in those who have liver problems. Please talk to your physician.

Kidney
CautionIstamet D XR 1000 Tablet Dosage should be used with caution by those who have renal disease. It could be essential to adjust the dosage. Please consult your physician. But it is not recommended for people with serious kidney problems.
Chemical Group | Biguanide, Triazolopiperazine derivative, and C-glycosyl |
Addictive | No |
Medication Class | Biguanides, dipeptidyl peptidase-4 (DPP-4) inhibitor, and Sodium-glucose co-transporter 2 (SGLT2) inhibitor |
Action Class/Category | Type II Diabetes Mellitus |
Swift Advice
- Keep up a healthy diet and get regular exercise to help reduce blood sugar levels.
- To reduce the likelihood of experiencing stomach distress, take it with food.
- Compared to other diabetic treatments, this medication’s side effects are less frequent. The weight increases as a result of hypoglycemia.
- When utilizing the tablet, renal function tests should be carried out often.
- When taking this drug, exercise caution and keep a close eye on your blood sugar levels. Get in touch with your doctor right away if you experience nausea, vomiting, fast or labored breathing, or stomach pain. These signs could point to lactic acidosis, a rare but potentially deadly condition brought on by an excess of lactic acid in the blood.
- It’s a good idea to have sugar candies on hand in case your blood sugar dips suddenly.
Can I take sitagliptin, metformin, and dapagliflozin together?
Yes under medical guidance sitagliptin, metformin, and dapagliflozin together in one product Istamet D XR 1000 Tablet can be taken to manage type 2 diabetes.
When is the best time to take dapagliflozin metformin and sitagliptin?
Take dapagliflozin, metformin, and sitagliptin exactly as prescribed by your physician. Usually, it is consumed with food. You should keep taking it at the same time every day for the entire suggested duration. Notify your physician if you cease taking your medication.
How long does it take for Istamet D XR 1000 to start working?
While Istamet D XR 1000 may start to exhibit effects as soon as a week, it can take months for it to fully manifest its antidiabetic effect.
Can Istamet D XR 1000 cause hypoglycemia?
Low blood sugar, or hypoglycemia, can be caused by Istamet D XR 1000. When this medicine is taken with other diabetes treatments (such as glipizide, glyburide, or insulin), this happens more frequently. Before symptoms of low blood sugar cause unconsciousness, it’s critical to treat them. Speak with your doctor if you have symptoms like shakiness, sweating, a fast heartbeat, or fatigue in order to prevent harmful side effects.
What factors to consider when choosing an Istamet D -XR 1000 Tablet?
Take into account elements such as cold chain shipment capabilities, medical warehouses, supply chain hubs, and safety packaging provided by the wholesaler. All these attributes are embodied by The Lotus Biotech, which provides excellent products for a range of medical ailments. Utilize our online marketplace to locate and purchase premium drugs in large quantities, including antidiabetic drugs like sitagliptin, metformin, and dapagliflozin. Please contact us at info@thelotusbiotech.com for a personalized estimate based on your needs and quantities.