Description
Istamet XR Tablet
Medicine | Istamet XR Tablet |
Marketed By | Sun Pharmaceutical Industries Ltd |
Active Ingredient | Sitagliptin 100mg and Metformin 1000mg |
Storage | Store below 30°C |
Consume Type | Oral |
Ondero Met 5/500mg Tablet – Introduction
Istamet XR 100/1000 Tablet – Introduction
Istamet XR 100/1000 is a high-end drug that combines metformin and sitagliptin, two powerful components. This potent antidiabetic drug helps lower increased blood sugar levels in people with type II diabetes. Metformin decreases the amount of glucose produced by the liver, raises insulin sensitivity, and decreases intestinal glucose absorption. Sitagliptin increases two incretin hormones: GLP-1 and GIP. By encouraging pancreatic beta cells to secrete more insulin and preventing pancreatic alpha cells from secreting glucagon, these incretins reduce blood sugar levels.
How Istamet XR Tablet Works: A Closer Look
In order to lower blood sugar levels, metformin primarily inhibits hepatic gluconeogenesis and glucagon action. It lowers the amount of glucose your body absorbs from food and your liver produces. Dipeptidyl peptidase-4 is inhibited by sitagliptin (DPP-4). It works by blocking the DPP-4 enzyme, which causes an increase in incretin hormone levels (such GLP-1 and GIP). By causing pancreatic alpha cells to release less glucagon and stimulating pancreatic beta cells to produce more insulin, these incretins reduce blood sugar levels.
Use
Mangement of Type II Diabetes Mellitus
Istamet XR Tablet – The Benefits
In Mangement of Type II Diabetes Mellitus
This medication helps people with type II diabetes manage their increased blood sugar levels. This drug should be used with dietary modifications and exercise for optimal outcomes. By controlling blood sugar levels, problems like kidney damage, nerve problems, blindness, amputations, and sexual dysfunction can be avoided. Reducing the chance of heart attacks and strokes is another benefit of effective diabetes control.
Istamet XR Tablet – A Usage Guide
- Pay attention to your doctor’s advice regarding the dosage and timing of this medication’s administration. Swallow the tablet whole along with some water. Never chew them. It must be taken in conjunction with food to avoid stomach upset.
- When you remember to take the missed dose, do so right away. However, if it’s almost time for your next prescription, skip the one you skipped and resume your regular regimen. It is not recommended to take two dosages at once.
Istamet XR Tablet – Side Effects
The majority of the side effects fade away as your body adjusts to the medication. If they persist longer than expected it is advisable to book an appointment with your doctor.
Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Stomach ache
- Altered appetite
- A metallic taste in the mouth
[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s side effects, refer to the official prescription information or consult your healthcare provider.]
Istamet XR Tablet – A Guide to Safety

Alcohol
Unsafe
To avoid lactic acidosis, a potentially dangerous situation brought on by an accumulation of lactic acid in the body, do not drink alcohol while taking the tablet.
Pregnancy
Consult your doctor
It might not be appropriate to use when pregnant. Human studies are rare. Nonetheless, studies conducted on animals have indicated detrimental impacts on the developing fetus. Your doctor will weigh the benefits against any potential downsides before prescribing.
Breastfeeding
Consult your doctor
Most certainly, using it while nursing is unsafe. There is little human data to suggest that the medicine may harm the child because it can get into the breast milk.
Driving
Caution
If your blood sugar level is too high or too low, it could damage your ability to drive. If you experience these symptoms, don’t drive.
Liver
Unsafe
It is best to avoid taking it in individuals who have liver issues due to the possibility of adverse effects. Kindly speak with your doctor.
Kidney
Caution
Those with kidney conditions should use it cautiously. It could be necessary to change the medication’s dosage. Kindly speak with your physician. However, in those with severe kidney disease, however, it is not advised.
Fact Box
Chemical Group | Biguanide and Triazolopiperazine derivative |
Addictive | No |
Medication Class | Biguanides and dipeptidyl peptidase-4 (DPP-4) inhibitor |
Action Class/Category | Type II Diabetes Mellitus |
Swift Advice
- Take it to help lower blood sugar levels along with a healthy diet and regular exercise.
- Eat it with food to lessen the chance of getting upset stomach.
- Compared to other diabetic drugs, hypoglycemia and weight gain are fewer common side effects.
- When taking this medication, be sure to monitor your blood sugar levels closely.
- See your doctor as soon as possible if you experience nausea, vomiting, rapid or deep breathing, or stomach discomfort. These signs may point to lactic acidosis, an uncommon but potentially fatal condition caused by an overabundance of lactic acid in the blood.
- Renal function tests should be carried out often while using this drug.
- It’s a good idea to have sugar candies on hand in case your blood sugar decreases without warning.
Does sitagliptin and metformin help you lose weight?
Metformin and sitagliptin have been shown in a few small studies to inhibit weight reduction, although there is no concrete evidence to support this claim. If you find that you are unexpectedly losing weight while undergoing therapy, consult your physician.
When is the best time to take Istamet XR?
Follow your doctor’s instructions regarding the best times and amounts to take Istamet XR. Consume it with meals to reduce the possibility of experiencing stomach distress. For optimal effects, it should be taken every day at the same time
Should I take Istamet XR before or after food?
Take Istamet XR with food to lessen the chance of suffering an upset stomach. It should be taken at the same time each day for the best results.
How long does it take for sitagliptin and metformin to lower blood sugar?
It may take months for the effects of metformin and sitagliptin in Istamet XR Tablet to fully manifest, even though they may start to show effects in as little as a week.
Where can Istamet XR Tablet be purchased in bulk?
You can purchase Istamet XR Tablet directly from reliable distributors and suppliers such as The Lotus Biotech. Utilize our online platform to search for and purchase high-quality drugs in large quantities. Depending on the quantity and your particular needs, contact us at info@thelotusbiotech.com for custom quotes.