Description
| Medicine | Poshope Injection |
| Marketed By | Abbott |
| Active Ingredient | Posaconazole 300mg |
| Storage | Store below 25°C, Do Not Freeze |
| Consume Type | Intravenous Infusion |
Poshope Injection- Introduction
Posaconazole injection belongs to the group of drugs called antifungals. It works by preventing the growth of fungus and is used to treat fungal infections. It eliminates fungus by rupturing the fungal cell membrane.
Adults with fungal infections, such as those brought on by Aspergillus, Fusarium, Chromoblastomycosis, Mycetoma, and Coccidioides, can benefit from the use of Poshope 300 Injection. This is especially true in cases when prior antifungals such as amphotericin B, itraconazole, or fluconazole have not worked as intended or have been stopped. It also cures untreated Candida-induced thrush.
Note: It is normally used in severe cases
How Poshope Injection Works: A Closer Look
Posaconazole injection dosage, like other azole derivatives, prevents the manufacture of ergosterol, a crucial component of fungal cell membrane, by blocking the enzyme lanosterol 14α-demethylase. This inhibition is the primary cause of fungal death.
Poshope Injection – Use
Treatment of Severe Fungal Infections
Poshope Injection – The Benefits
In the Treatment of Severe Fungal Infections
Posaconazole injection is used to treat invasive aspergillosis in adults and pediatric patients aged 13 and older. It’s also used for prophylaxis against invasive Aspergillus and Candida infections in severely immunocompromised patients, like those undergoing hematopoietic stem cell transplant (HSCT) or with hematologic malignancies experiencing prolonged neutropenia due to chemotherapy.
Poshope Injection – A Usage Guide
It will be administered in a hospital setting by a medical professional.
Poshope Injection – Side Effects
Most of the posaconazole 300 mg side effects fade away as your body adjusts to the medicine. If they persist longer than expected, it is advisable to book an appointment with your doctor.
Common Side Effects
- Stomach pain
- Constipation
- Diarrhea
- Nosebleeds
- Coughing
- Fever
- Headache
- Chills
- Shakiness
[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s side effects, refer to the official prescription information or consult your healthcare provider.]
Poshope Injection – A Guide to Safety
Alcohol
Consult your doctor
Regarding the impact of alcohol on posaconazole, nothing is known. Consult your doctor.
Pregnancy
Consult your doctor
This injection may pose risks to the fetus based on animal studies, but its effects on pregnant women are not fully understood. Women taking this medication should use effective contraception as advised by their doctor to prevent pregnancy.
Breastfeeding
Consult your doctor
There aren’t enough studies on women to assess the harm to the unborn child when taking this injection while nursing. Before using this drug whilst nursing, the doctor will assess the possible advantages against the potential disadvantages.
Driving
Caution
When injecting, you can experience lightheadedness, drowsiness, or impaired vision, which could impair your ability to operate machinery or drive a car. In the event that this occurs, call your doctor and refrain from operating any machinery or driving.
Liver
Caution
If you now have or have previously had liver issues. Blood tests can be necessary when using this medication.
Kidney
Caution
If you are using posaconazole, routine renal function monitoring may be required to enable early detection of reversible acute kidney injury.
Fact Box
| Chemical Group | Member of triazoles |
| Addictive | No |
| Medication Class | 14-alpha Demethylase Inhibitors |
| Action Class/Category | Fungal Infection |
Swift Advice
Before starting posaconazole therapy, consult your healthcare provider if you:
- Have had allergic reactions to antifungal medications like voriconazole, ketoconazole, fluconazole, or itraconazole.
- Have a history of liver issues; regular blood tests may be needed during treatment.
- Experience severe diarrhea or vomiting, as they may affect medication effectiveness.
- Have irregular heart rhythms (ECG), heart failure, or weakened heart muscles.
- Take note of all posaconazole contraindications advised by your healthcare provider.
- Ensure a certified medical professional administers it in a hospital setting.
- Follow your doctor’s instructions diligently.
- Disclose your medical history and current medications before use.
- Schedule regular liver and kidney function tests.
How long should Poshope injection be taken?
The duration varies depending on the type and severity of fungal infection. Initially, the injection is administered twice daily on the first day, followed by once-daily dosing. For invasive Aspergillosis, the loading dose is 300 mg intravenously twice daily on day one, followed by a maintenance dose of 300 mg intravenously once daily. Treatment typically lasts 6 to 12 weeks, as determined by your doctor.
How is posaconazole injection administered?
Posaconazole injection is administered intravenously, slowly, over 30 to 90 minutes. Initially, it’s infused twice daily on the first day, followed by a once-daily dosing. The treatment duration is determined by your doctor based on your condition.
What is the role of posaconazole in immunocompromised patients?
Posaconazole injection is used to prevent invasive Aspergillus and Candida infections in severely immunocompromised patients, including hematopoietic stem cell transplant recipients with graft-versus-host disease (GVHD) and those with hematologic malignancies experiencing prolonged neutropenia due to chemotherapy.
When is the best time to take posaconazole?
Posaconazole works most effectively when there is a consistent level in the bloodstream. To maintain this level, it’s important not to miss any doses and to take each dose at the same time daily. Under a doctor’s guidance, scheduling of your medication will be done.
Can I negotiate prices with poshope injection suppliers?
Absolutely, at The Lotus Biotech, a leading pharmaceutical supplier, we are open to negotiation. We provide the best deals on bulk orders that are budget-friendly for our customers. For further details, reach out to us at info@thelotusbiotech.com.
