Description
| Medicine | Verz 50mg Tablet |
| Marketed By | Dr Reddy’s Laboratories Ltd. |
| Active Ingredient | Voriconazole 50mg |
| Storage | Store below 30°C |
| Consume Type | Oral |
Verz 50mg Tablet – Introduction
Verz 50mg is used to treat a number of serious, occasionally fatal fungal infections of the mouth, throat, and lungs. It should not be used by anyone who is known to be allergic to it.
How Verz 50mg Tablet Works: A Closer Look
The mechanism of action of voriconazole 50 mg is the inhibition of 14 alpha-lanosterol demethylation, a critical step in the synthesis of fungal ergosterol, which is mediated by fungal cytochrome P-450. The fungus dies when this important intrinsic step is inhibited.
Note: It should be given mostly to individuals who have infections that are getting worse and could be fatal.
Verz 50mg Tablet Use
Treatment of Severe Fungal Infections
Verz 50mg Tablet – The Benefits
In the Treatment of Severe Fungal Infections.
By acting as a fungistatic agent, it guards against dangerous and perhaps fatal fungal infections.
Verz 50mg Tablet – A Usage Guide
Follow your doctor’s instructions on the dosage and duration of this medication. Take it all in at once. Never shatter, eat, or crush it. It must be taken either one hour prior to or one hour after a meal.
Verz 50mg Tablet – Side Effects
The majority of the Voriconazole 50 mg side effects fade away as your body adjusts to the medicine. If they persist longer than expected, it is advisable to book an appointment with your doctor.
Common Side Effects
- Visual impairment
- Rash
- Breathing difficulties
- Elevated liver enzymes
- Nausea,
- Vomiting, diarrhoea
- Headache
- Swelling of the extremities
- Stomach pains
[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s side effects, refer to the official prescription information or consult your healthcare provider.]
Verz 50mg Tablet – A Guide to Safety
Alcohol
Consult your doctor
Voriconazole levels may rise or fall in response to the combination with alcohol because of modifications in liver metabolism. Avoid combining voriconazole with alcohol.
Pregnancy
Unsafe
Voriconazole has been shown to be teratogenic in animals, even at low dosages. It is categorised as pregnancy category D on the USFDA list and is strongly urged to be avoided during pregnancy. It is not recommended to use this medicine while pregnant unless the advantages outweigh the hazards to the growing baby.
Breast feeding
Consult your doctor
Regarding the use of voriconazole while nursing, no information is available. If the mother need voriconazole, it is not a reason to cease nursing. Until more information is available, it could be preferable to use an alternative medicine, especially if you are nursing a newborn.
Driving
Unsafe
It may result in bothersome light sensitivity or blurriness of vision. Don’t drive or operate any tools or machinery while you’re affected. If you encounter this, get in touch with your physician.
Liver
Caution
Jaundice and other liver disease symptoms have been connected to it, as well as elevated abnormal liver function test findings. Only in cases of severe liver impairment, where the benefits of voriconazole outweigh the potential dangers, should it be used.
Kidney
Caution
According to current guidelines, people with severe renal impairment should not receive the medication. Consult your doctor.
Fact Box
| Chemical Group | Triazole antifungal |
| Addictive | No |
| Medication Class | 14-alpha Demethylase Inhibitors |
| Action Class/Category | Fungal Infection |
Swift Advice
- Take this medication at least an hour before or after eating on an empty stomach.
- Avoid consuming more or less than is suggested or prescribed.
- Should you encounter any unfavourable side effects, speak with your physician.
- Make sure the entire course of treatment is finished. Don’t stop taking this medication without first talking to your doctor.
- Vision problems like light sensitivity and blurriness can be brought on by this medication. During the day, put on sunglasses to shield your eyes from harsh light.
- Have a regular liver and kidney function test.
Is Verz 50mg Tablet safe for long-term use?
People with photosensitivity skin reactions have reported developing squamous cell carcinoma and melanoma on their skin during long-term therapy of Verz 50mg Tablet. Your doctor will communicate when to stop the therapy.
What is the shelf life of Voriconazole 50mg?
The shelf life of Voriconazole 50mg tablets is typically 24 months (2 years) when stored under the recommended conditions.
How long does voriconazole stay in your system?
The drug takes four or five half-lives to exit the body. Around 80% of the whole dose of voriconazole is recovered as metabolites in the urine, with an approximate 6-hour elimination half-life.
How effective is Verz 50mg Tablet?
Voriconazole tablets are highly effective in treating a variety of serious fungal infections, including invasive aspergillosis, candidemia in non-neutropenic patients, and severe infections caused by Scedosporium and Fusarium species. Its effectiveness is well-documented in clinical trials and practice, making it a preferred choice for treating life-threatening fungal infections.
In one trial, the voriconazole group experienced an 88% success rate (symptoms resolved or improved).
Is there any international exporter of Verz 50mg Tablet?
Yes. The Lotus Biotech is an international exporter of top-notch pharmaceuticals from India, including Verz 50mg Tablet. For bulk orders, contact us at info@thelotusbiotech.com.
