Votrient 400mg Pazopanib Tablets

Votrient 400mg Pazopanib Tablets

Votrient 400 is an anti cancer medication primarily used for the treatment of advanced renal cell carcinoma (kidney cancer) and soft tissue sarcoma. Its active salt, pazopanib, works by inhibiting the growth of blood vessels that supply tumors, thereby slowing down their progression and reducing their size.

  • Manufactured By : Glaxo SmithKline Pharmaceuticals Ltd
  • Salt Composition : Pazopanib 400mg
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Votrient 400mg Pazopanib Tablets


Glaxo SmithKline Pharmaceuticals Ltd

Active Ingredient 

Pazopanib 400mg 


Store below 30 °C.

Consume Type 



Complete Handbook on Votrient 400mg Pazopanib: Usage and Insight 

Votrient 400mg Pazopanib Tablets: Introduction

Votrient 400mg Pazopanib tablets are a targeted cancer treatment that is used to treat advanced kidney cancer and certain types of advanced soft tissue sarcoma. It inhibits tumor growth and angiogenesis by acting as a potent and selective inhibitor of multiple receptor tyrosine kinases.

How Votrient 400mg Pazopanib Tablets Work: A Closer Look

Pazopanib, a tyrosine kinase inhibitor (TKI) and a targeted cancer drug, is contained in Votrient 400mg Tablets. Tyrosine kinases are enzymes found in cells that promote cancer cell growth. Pazopanib is a multi-tyrosine kinase inhibitor, which means it inhibits multiple of these proteins. By doing this, it stops cancer cells from growing the blood vessels that are required for their growth—a therapeutic strategy called anti-angiogenesis.

Votrient 400mg Pazopanib Tablets: Use

  • Advanced kidney cancer (renal cancer)
  • Some types of soft tissue sarcoma


Votrient 400mg Pazopanib Tablets: The Benefits 

  • Kidney cancer 

The Votrient 400 mg Tablet is used to treat symptoms of kidney cancer, including blood in the urine, persistent back pain, weight loss, fatigue, and appetite loss. It stops the spread of the disease by slowing the growth and division of cancer cells.  Adhere strictly to your doctor’s instructions for a quick and full recovery.

  • Soft tissue sarcoma

Soft tissue sarcoma is a type of cancer that begins in tissues such as muscles and bones. Votrient 400mg Tablet stops the growth and division of cancer cells in this type of cancer. Follow your physician’s advice to the letter and inform them of any uncomfortable side effects.

Votrient 400mg Pazopanib Tablets: A Usage Guide

Regarding the recommended dosage and duration of this drug, heed the advice of your physician. Don’t chew, crush, or break the pill; instead, swallow it whole. It’s recommended to take it empty-handed.

Votrient 400mg Pazopanib Tablets: Side Effects

Most adverse effects are generally temporary and go away as your body adjusts to the medicine. See your doctor for advice if any side effects are severe or persistent.

Common Side Effects 

  • Headache
  • Nausea
  • Vomiting
  • Musculoskeletal (bone, muscle, or joint) pain
  • Fatigue
  • Change in color of hair
  • Diarrhea
  • High blood pressure
  • Decreased appetite
  • Weight loss
  • Taste change
  • Abnormal skin pigmentation
  • Hair discoloration
  • Tumor pain
  • Breathlessness

[Note: There are a number of negative effects that drugs can have.  To find out everything there is to know about a particular medication’s side effects, visit the official website or consult your physician.

Votrient 400mg Pazopanib Tablets – A Guide to Safety 


Consult Your Doctor

It is unclear if it is safe to take a 400 mg tablet of Votrient along with alcohol. For advice on consuming alcohol while taking this medication, speak with your doctor.



Pregnant women may be at risk from this medication. Pregnancy should be avoided both while taking this medication and for at least two weeks after therapy ends. Before starting therapy, discuss safe contraceptive options with your doctor or nurse. 


Consult Your Doctor

It is unknown how this medication enters breast milk. Doctors usually advise against breastfeeding during this course of medication.



Votrient 400mg Tablet may impair your eyesight, make you drowsy and dizzy, or decrease your level of attentiveness. If you experience any of these symptoms, you should not drive.


Safe, If Prescribed

You may experience mild hepatic changes while on therapy; these changes are typically asymptomatic. When the therapy is finished, these changes usually return to normal. Your doctor will check your liver function on a regular basis with blood tests.


Safe, If Prescribed

During testing, your healthcare provider may detect trace levels of protein in your urine; these are normally undetectable. If elevated protein levels are discovered, additional testing to evaluate your kidney function may be required.

Fact Box

Chemical Group 

Alkyldiarylamines Derivative



Medication Class

Anti Neoplastic

Action Class/Category 

Tyrosine Kinase Inhibitor

Swift Advice

  1. Engaging in physical activities like walking or swimming for 20-30 minutes can strengthen your muscles, reduce fatigue, aid in weight loss, and boost your overall strength.
  2. Incorporating yoga and relaxation techniques into your routine can improve both physical and mental health while reducing stress levels.
  3. To maintain a healthy weight, practice regular, low-impact exercises, and follow a balanced diet.
  4. Adequate sleep is essential for overall health, cognitive function, and attention span.
  5. To unwind and relax, consider activities like meditation, reading, taking a warm bubble bath, or listening to soothing music.
  6. Consume foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  7. Include fiber-rich foods like beans, peas, lentils, whole grains, nuts, and seeds in your diet to support better digestion.
  8. Avoid smoking and excessive alcohol consumption for better health.
  9. If you experience swelling in your lower legs, fast heartbeats, or difficulty breathing, seek immediate medical attention, as it could be a sign of a heart problem.
  10. Note that Votrient 400mg Tablet may lead to bleeding, so inform your doctor if you notice blood in your urine or stool.

Frequently Asked Questions: Votrient 400mg Pazopanib Tablets

Q: Is Votrient 400mg Tablet a chemotherapy medicine?

A: Votrient 400mg Tablet is not a traditional chemotherapy medication. It is a member of the group of drugs known as tyrosine kinase inhibitors. The mechanism of action of Votrient 400mg Tablet is to stop the activity of proteins involved in the development and metastasis of cancer cells.

Q: How should I take Votrient 400mg Tablet?

A: Take one Votrient 400 mg tablet by mouth every day, or as prescribed by your physician. Do not break or crush the tablets; instead, swallow them whole with water. This may raise the risk of side effects and alter how the medication is absorbed.

Q: Can Votrient 400mg Tablet be taken with food?

A: Take Votrient 400mg Tablet on an empty stomach, at least 1 hour before or 2 hours after eating. If taken with food, the dosage may need to be increased, which may result in more side effects.

Q: How will I know if Votrient 400mg Tablet is helping me?

A: The length of time you must take Votrient 400mg Tablet varies from person to person. The doctor will closely monitor you and will be able to better estimate how long the medicine must be taken. Do not stop taking it without first consulting your doctor. It must be taken for as long as it is effective and tolerable.

Q: Are there any food restrictions while I’m taking Votrient 400mg Tablet?

A: Yes, because grapefruit may interfere with how the Votrient 400mg Tablet works in your body, you should avoid grapefruit and grapefruit juice while taking it. Find out from your doctor which other foods you should stay away from.

Q: How long I have to take Votrient 400mg Tablet?

A: The length of time you must continue taking Votrient 400mg Tablets depends on your specific situation. The doctor can better determine how long the medication must be administered because they are keeping a close eye on you. Never stop taking it without first consulting your doctor. As long as it works and you can bear it, you must take it.

Q: What is the most important information I need to know about Votrient 400mg Tablet?

A: Votrient 400 mg Tablet has the potential to cause serious or fatal liver damage. Inform your doctor if you have or have had liver problems. Call your doctor right away if you notice any of the following symptoms: yellowing of the skin or eyes; dark urine; excessive tiredness; nausea; vomiting; loss of appetite; discomfort in the upper right portion of the stomach; or unusual bleeding or bruises.