Description
| Medicine | Istamet D-IR 5/50/500 Tablet |
| Marketed By | Sun Pharmaceutical Industries Ltd |
| Active Ingredient | Dapagliflozin 5mg, Sitagliptin 50mg and Metformin 500mg |
| Storage | Store below 30°C |
| Consume Type | Oral |
Istamet D-IR 5/50/500 Tablet – Introduction
Stamet D IR 5/50/500 contains sitagliptin, metformin, and dapagliflozin—used to manage type 2 diabetes. It works by lowering sugar from the liver, improving insulin use, boosting insulin release, and helping the body flush out extra sugar through urine. Together, these actions help reduce high blood sugar levels effectively.
How Istamet D-IR 5/50/500 Tablet Works: A Closer Look
Metformin mainly inhibits the effect of glucagon and hepatic gluconeogenesis, an intrinsic mechanism that elevates blood glucose levels, in order to lower blood sugar. Moreover, sitagliptin inhibits dipeptidyl peptidase-4 (DPP-4), causing an increase in incretin hormone levels (such as GLP-1 and GIP). By encouraging pancreatic beta cells to produce more insulin and decreasing the amount of glucagon released by pancreatic alpha cells, these incretins lower blood sugar. Dapagliflozin decreases blood glucose levels and increases urine glucose excretion by blocking the sodium-glucose co-transporter 2 (SGLT2).
Use
Mangement of Type II Diabetes Mellitus
Istamet D-IR 5/50/500 Tablet – The Benefits
In Management of Type II Diabetes Mellitus
One drug that helps persons with type II diabetes better control their elevated blood sugar levels is Istamet D IR 5/50/500. This medication should be used in conjunction with dietary changes and physical activity for the best results.
Maintaining healthy blood sugar levels can help prevent issues such as sexual dysfunction, amputations, blindness, nerve damage, and kidney illness. Another advantage of good diabetes management is a decreased risk of heart attacks and strokes.
Istamet D-IR 5/50/500 Tablet – A Usage Guide
- Pay attention to your doctor’s advice regarding the dosage and timing of this medication’s administration. Swallow the tablet whole along with some water. Never chew them. It must be taken in conjunction with food to avoid stomach upset.
- When you remember to take the missed dose, do so right away. However, if it’s almost time for your next prescription, skip the one you skipped and resume your regular regimen. It is not recommended to take two dosages at once.
Istamet D-IR 5/50/500 Tablet – Side Effects
The majority of the side effects fade away as your body adjusts to the medication. If they persist longer than expected it is advisable to book an appointment with your doctor.
Common Side Effects
- Nausea
- Urinating more frequently than usual
- Vomiting
- Thrush
- Back pain
- Metallic taste in the mouth
- Diarrhea
- Stomach ache
- Altered appetite
[Note: Different drugs can cause varying side effects. To get accurate information about a medication’s side effects, refer to the official prescription information or consult your healthcare provider.]
Istamet D-IR 5/50/500 Tablet – A Guide to Safety
Alcohol
Unsafe
To avoid lactic acidosis, a potentially dangerous disease brought on by an accumulation of lactic acid in the body, do not drink alcohol while using Istamet D IR 5/50/500 dosage.
Pregnancy
Consult your doctor
It might not be suitable to use when expecting. Studies involving humans are uncommon. However, research on animals has demonstrated negative effects on the growing fetus. Your physician will assess the advantages above any possible drawbacks before prescribing.
Breastfeeding
Consult your doctor
It might be dangerous to use it while nursing. Because the medication can enter breast milk, there is a lack of human data to support the idea that it could harm the infant.
Driving
Caution
When your blood sugar levels are too high or too low, driving can be risky. Steer clear of driving if any of these symptoms apply to you.
Liver
Unsafe
Because of the potential for negative consequences, it is advised to avoid taking the tablet in those who have liver problems. Please talk to your physician.
Kidney
Caution
Those with kidney conditions should use Istamet D IR Tablet Dosage cautiously. It could be necessary to change the dosage. Kindly speak with your physician. However, in those with severe kidney disease, however, it is not advised.
Fact Box
| Chemical Group | Biguanide, Triazolopiperazine derivative, and C-glycosyl |
| Addictive | No |
| Medication Class | Biguanides, dipeptidyl peptidase-4 (DPP-4) inhibitor, and Sodium-glucose co-transporter 2 (SGLT2) inhibitor |
| Action Class/Category | Type II Diabetes Mellitus |
Swift Advice
- Consume a healthy diet and engage in regular exercise to help lower blood sugar levels.
- To reduce the possibility of experiencing an upset stomach, take it with food.
- The side effects of this medication are less frequent than those of other diabetes therapies. Weight increases with hypoglycemia.
- When using the tablet, regular renal function testing should be done.
- When taking this medication, exercise caution and closely monitor your blood sugar levels. Call your doctor right away if you suffer from nausea, vomiting, quick or deep breathing, or stomach pain. These signs could point to lactic acidosis, a rare but potentially deadly condition brought on by an excess of lactic acid in the blood.
- It’s a good idea to have sugar candies on hand in case your blood sugar dips suddenly.
- Follow Istamet D IR 5/50/500 instructions exactly as described by your doctor.
Is Istamet D IR 5/50/500 suitable for elderly patients?
Patients above 75 years of age should not use Istamet D IR 5/50/500. But whether or not you can take the medication will be determined by your doctor. After analyzing the risk-benefit ratio, they are able to prescribe.
How does Istamet D IR 5/50/500 impact cardiovascular health?
Istamet D IR 5/50/500 activates AMPK phosphorylation, reducing oxidative stress and inflammatory cytokines while increasing eNOS activity. It protects cardiovascular health by reducing cardiac apoptosis, hypertrophy, and fibrosis and lowers HbA1c, body weight, BP, and serum uric acid.
How effective is Istamet D IR 5/50/500 for diabetes management?
Istamet D IR 5/50/500 is effective for diabetes management under medical guidance. It contains dapagliflozin, metformin, and sitagliptin, potent antidiabetic drugs that help people with type II diabetes lower their increased blood sugar levels.
What should be avoided while taking Istamet D IR 5/50/500 Tablet?
Avoid the following things when to prevent possible Istamet D IR 5/50/500 interactions:
- Alcohol: It can cause hyperglycemia or hypoglycemia in diabetics.
- Some Foods: Steer clear of processed foods and foods high in sodium, sugar, trans fats, and saturated fats.
- Specific Drugs: Avoid diuretics and prescription medications if you have high blood pressure or heart problems.
Where can Istamet D-IR 5/50/500 Tablet be purchased in bulk?
Bulk orders for the Istamet D-IR 5/50/500 Tablet can be placed directly with reputable distributors and suppliers like The Lotus Biotech. Use our web-based platform to locate and buy high-quality medications in bulk. For an estimate customized to your requirements and quantity, please get in touch with us at info@thelotusbiotech.com.
