Carbophage G1 Forte Tablet

Carbophage G1 Forte Tablet

Carbophage G1 Forte Tablet PR combines metformin and glimepiride in strengths of 1000mg and 1mg, respectively. It is used to manage type 2 diabetes mellitus and aid in the control of blood sugar levels.

Complete Handbook on Carbophage G1 Forte Tablet PR: Usage and Insight

MedicineCarbophage G1 Forte Tablet PR
Marketed ByMerck Ltd
Active IngredientGlimepiride 1mg and Metformin 1000mg
StorageStore below 30°C
Consume TypeOral 

Carbophage G1 Forte Tablet PR – Introduction

Carbophage G1 Forte Tablet PR by Merck Ltd. combines two antidiabetic agents: Glimepiride 1mg + Metformin 1000mg. This extended-release tablet is designed to provide a controlled release of medication, helping to maintain stable blood glucose levels over an extended period. It is prescribed for patients with type 2 diabetes mellitus when diet, exercise, and single-agent treatment do not result in adequate glycemic control. The tablet’s dual-action mechanism enhances insulin secretion and improves insulin sensitivity, making it an effective option for comprehensive diabetes management.

How Carbophage G1 Forte Tablet PR Works: A Closer Look

Glimepiride (1mg):

Glimepiride is a sulfonylurea that works by stimulating the release of insulin from the pancreatic beta cells. It enhances insulin secretion in response to meals and improves the body’s ability to use insulin effectively.

Metformin (1000mg):

Metformin belongs to the biguanide class of medications and primarily acts by decreasing hepatic glucose production. It also increases insulin sensitivity in peripheral tissues (muscle and fat), thereby enhancing glucose uptake and utilization.


In the management of Type 2 Diabetes Mellitus 

(Used as an adjunct to diet and exercise to improve glycemic control in adults. May be used when monotherapy with either Glimepiride or Metformin is insufficient.)

Carbophage G1 Forte Tablet PR – The Benefits 

  • Improved Glycemic Control:

The combination of Metformin and Glimepiride provides a synergistic effect, leading to better blood sugar control compared to monotherapy with either agent. By enhancing insulin secretion and sensitivity, it helps reduce the risk of blood sugar spikes after meals.

  • Convenient Dosing:

The extended-release formulation in Carbophage G1 Forte Tablet Dosage allows for once-daily dosing, which can improve patient compliance and convenience. It also targets different aspects of diabetes pathophysiology, providing a comprehensive approach to diabetes management.

  • Cardiovascular Benefits:

Metformin has been shown to have cardiovascular benefits, which can be advantageous for diabetic patients at risk of cardiovascular disease.

  • Weight Neutral or Weight Loss:

Metformin is associated with weight neutrality or modest weight loss, which benefits overweight or obese diabetic patients.

Carbophage G1 Forte Tablet PR – A Usage Guide

  • Take the medication exactly as prescribed by your healthcare provider. Do not alter or stop the prescribed Carbophage G1 Forte Tablet Dosage without consulting your doctor. Usually taken once daily with the first main meal of the day (breakfast or dinner) to reduce the likelihood of gastrointestinal side effects.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break it. It is an extended-release formulation, and altering its form may affect the controlled release of the medication.

Carbophage G1 Forte Tablet PR – Side Effects

Most adverse effects disappear when your body gets used to the medication and doesn’t require medical attention. See your physician if they continue or if you have concerns about them.

Common Side Effects

  • Hypoglycemia (Low Blood Sugar)
  • Nausea and Vomiting
  • Diarrhea
  • Abdominal Pain, and Bloating
  • Weight Gain
  • Edema (swelling)
  • Headache
  • Fatigue or Weakness
  • UTI

Rare but serious side effects include Lactic Acidosis, Allergic reactions, Hepatic Impairment, and Hemolytic Anemia. Always inform your healthcare provider about any side effects you experience, especially if they are severe or persistent. Your doctor may adjust the dosage or suggest ways to manage side effects

[Note: Various medications can lead to different side effects. For precise details about a particular drug’s specific side effects, consult the official prescribing information for that medication or seek advice from your healthcare provider.]


Carbophage G1 Forte Tablet PR – A Guide to Safety




When using Carbophage G1 Forte Tablet PR, it is important to avoid alcohol in order to prevent the occurrence of a dangerous condition called lactic acidosis, which involves the buildup of lactic acid in the body.



Consult Your Doctor

It may not be advisable to use during pregnancy. There is limited research on humans. However, studies on animals have shown adverse effects on fetal development. Your doctor will evaluate the benefits and potential risks before prescribing it.


  Breast feeding


It’s probably unsafe to use while nursing. The baby could be adversely affected because the medication can pass into the breastmilk, based on the limited available information. It’s important to seek advice from your doctor.




If your blood sugar is too low or too high, it might impair your driving ability. If you experience these symptoms, refrain from driving.




Patients with liver disease should use Carbophage G1 Forte Tablet PR cautiously. They may require dose adjustment, so it’s important to consult with a doctor. In cases of mild to moderate liver disease, it’s typically initiated with a low dose, while it’s not advised for use in patients with severe liver disease.




People with kidney issues should be cautious when using it. Adjusting the medication dosage may be necessary. Please consult your doctor. However, Carbophage G1 Forte Tablet PR is not recommended for those with severe kidney disease.

Fact Box

Chemical GroupBiguanide and Sulfonylurea class
Medication ClassBiguanide and ATP-sensitive potassium channel blocker
Action Class/CategoryAntihyperglycemic agent (Anti-Diabetic)

Swift Advice 

  • Take the medication exactly as your doctor prescribes, including the dose and duration.
  • Monitor your blood sugar level regularly.
  • Take Carbophage G1 Forte Tablet PR with the first main meal of the day to minimize gastrointestinal side effects and improve the medication’s effectiveness. Skipping meals can increase the risk of hypoglycemia, so make sure to eat regular, balanced meals.
  • Be aware of the risk of low blood sugar, especially when taking this medicinal combination of metformin and glimepiride with other diabetes medications, alcohol, or if you miss a meal. Symptoms include cold sweats, cool pale skin, tremors, and anxiety. Carry sugary food or juice in case of hypoglycemia.
  • Use caution if you have kidney or liver issues, as these conditions can affect how the medication works. Your doctor may need to adjust your dose.
  • Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The medication may need to be adjusted or changed.
  • Inform your doctor about weight gain, shortness of breath, irregular heartbeat, or any abnormal swelling.

Frequently Asked Questions

Can you take glimepiride and metformin together?

Yes, glimepiride and metformin can be taken together. In fact, combination medications like Carbophage G 1 Forte Tablet PR contain both glimepiride and metformin to help control blood sugar levels in patients with type 2 diabetes more effectively. This combination works synergistically, with glimepiride stimulating insulin release and metformin improving insulin sensitivity and reducing glucose production in the liver.

Can glimepiride and metformin be taken together twice a day?

The dosing regimen for glimepiride and metformin can vary based on individual patient needs and the prescribed formulation. Some combination medications are designed for once-daily use, while others may be taken twice daily. Always follow your healthcare provider’s instructions regarding how often to take your medication. If separate tablets are prescribed, your doctor might recommend taking them with meals to reduce the risk of side effects and improve efficacy.

What should be avoided when taking glimepiride and metformin?

When taking glimepiride and metformin, avoid or limit alcohol consumption as it can increase the risk of lactic acidosis and affect blood sugar levels. Do not skip meals to prevent hypoglycemia. Inform your healthcare provider about all medications you are taking to avoid interactions. Stay well-hydrated, especially if you experience gastrointestinal side effects like diarrhea. Do not crush, chew, or break extended-release tablets to maintain their controlled release properties.

How long can you stay on glimepiride and metformin?

You can stay on glimepiride and metformin for as long as they effectively control your blood sugar levels without causing significant side effects. Diabetes management is typically a long-term process, and many patients may take these medications for years or even a lifetime. Regular monitoring and follow-up with your healthcare provider are essential to ensure that the medication continues to be effective and to make any necessary adjustments. Your treatment plan may be modified over time based on your response and changes in your health condition.

From where to buy Carbophafe G1 Forte Tablet in bulk?

Medications containing the combination of metformin and glimpride can be purchased from India’s trusted and reputable exporters and suppliers of pharmaceutical products, The Lotus Biotech. We are an active Carbophage G1 Forte Tablet Wholesale Dealer. Contact us today to get the best deals!